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The Appetite Reset

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What to expect

Appetite is not a test of willpower, but a biological system shaped by the brain, gut, hormones and the world around us. The rise of GLP-1 medications, including Ozempic, Mounjaro and Wegovy, has brought this into sharp focus, but one crucial question remains: how do you eat to support long-term health?

In The Appetite Reset, leading nutritionist and medical scientist Dr Federica Amati reveals how modern diets disrupt our natural signals, and how to restore them. Blending cutting-edge science with clear advice and recipes, she offers practical strategies to protect metabolism, master appetite and build a sustainable relationship with food.

Whether you want to understand your appetite, are taking GLP-1s, or adjusting to life afterwards, this is your essential guide to eating well.

Includes a foreword from Professor Tim Spector


'An interesting and informative exploration of the medication everyone is talking about - the GLP-1s- and the fascinating science behind their impact' - Dr Jack Mosley

'A timely and balanced look at appetite, nutrition and the rise of GLP-1 therapies that's actually grounded in science, not simply hype!' - Dr Hazel Wallace


© Federica Amati 2026 (P) Penguin Audio 2026

Critics Review

Cuts through the hype to explain what GLP-1 appetite drugs really mean for your long-term health
Professor Tim Spector
We’ve spent decades blaming people for their appetite instead of understanding it. The Appetite Reset shifts the focus back to biology - gut, metabolism, hormones - and makes modern appetite science practical!
Dr. Karan Rajan
In a time of extraordinary medical innovation and extraordinary confusion, Dr. Amati offers clarity. She explains the promise of GLP-1 therapies without overstating them, and reminds us that muscle, nutrition, and movement remain non-negotiable with these therapies. This book reframes weight loss as a question of metabolic health, function, and longevity. It is thoughtful, evidence-based, and deeply practical
Stuart Phillips, PhD
Dr Federica Amati translates complex metabolic science into a highly practical and empowering insights. A very timely and important book
Liz Earle MBE
What I value most about this book is its ability to hold nuance. Written from a nutritionist’s standpoint, it explores GLP-1s within the wider context of metabolic health, dietary patterns and clinical experience. It avoids extremes, acknowledges the science, and reinforces that meaningful health outcomes are built on more than a prescription alone
Rhiannon Lambert, Sunday Times Best Selling Author and Nutritionist
Longevity isn’t about willpower. It’s about shaping your environment and biology so the healthy choice is the easy choice. The Appetite Reset takes that evidence and translates it into practical action
Dan Buettner - National Geographic Fellow and #1 New York Times Bestselling author of the Blue Zones.
Smart, compassionate and deeply practical. The Appetite Reset is exactly the kind of science-driven nutrition guidance we need right now
Dr Will Bulsiewicz
The Appetite Reset offers a timely and thought-provoking exploration of how appetite, nutrition, and the new generation of GLP-1 therapies are reshaping the conversation around metabolic health
Dr Andrew Jenkinson
An interesting and informative exploration of the medication everyone is talking about - the GLP-1s- and the fascinating science behind their impact
Dr Jack Mosley
A timely and balanced look at appetite, nutrition and the rise of GLP-1 therapies that's actually grounded in science, not simply hype!
Dr Hazel Wallace
Author Dr Federica Amati
Narrator Dr Federica Amati
Duration 8 hours and 27 minutes
Release Date
ISBN 9781405995368
Format Audiobook
Publisher Penguin Books Ltd
Genre Coping with illness and specific health conditions, Diets and dieting, nutrition, Popular medicine and health: the human body
Availability AU, GB, IE

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